Thursday, February 08, 2007

How does SNP work?

1. In coding region of gene, if the SNP result in a non-synonymous mutation it would change the translated protein structure and function.
2. In coding region of gene, if the SNP is a synonymous mutation, the translated protein sequence might not be changed. But it is very interesting that the structure of protein would still have probabilty to be changed [17185560].

3. In promoter region, it would change the expression pattern of downstream genes[17053109 , 17053108].
4. In intron, ???
5. In other region, ???

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