Posttranscriptional Control of Gene Expression in Yeast -- McCarthy 62 (4): 1492 -- Microbiology and Molecular Biology Reviews
1. Does only mature mRNAs leave the nucleus?
It is generally agreed that, with very few exceptions, only mature mRNAs (bound by RNA-binding proteins [mRNPs]) leave the nucleus .
2. Does mRNA transportation associate with cytoskeleton?
The fact that mRNA is observed associated with microtubules and actin filaments suggests that these components of the cytoskeleton may be responsible for (selective) mRNA transport. Recent evidence also indicates that at least one yeast mRNA (ASH1) becomes localized within the cell by virtue of its association with the cytoskeleton (535).
3. How long is poly(A) tail in mRNA of Yeast?
At the 3' end, the mRNA carries a poly(A) tail (initially 60 to 90 adenylate residues in yeast.
1. Does only mature mRNAs leave the nucleus?
It is generally agreed that, with very few exceptions, only mature mRNAs (bound by RNA-binding proteins [mRNPs]) leave the nucleus .
2. Does mRNA transportation associate with cytoskeleton?
The fact that mRNA is observed associated with microtubules and actin filaments suggests that these components of the cytoskeleton may be responsible for (selective) mRNA transport. Recent evidence also indicates that at least one yeast mRNA (ASH1) becomes localized within the cell by virtue of its association with the cytoskeleton (535).
3. How long is poly(A) tail in mRNA of Yeast?
At the 3' end, the mRNA carries a poly(A) tail (initially 60 to 90 adenylate residues in yeast.
posted by Yiming Zhou at 8:36 PM
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